Immunogenicity of Recombinant Fiber-Chimeric Adenovirus Serotype 35 Vector-Based Vaccines in Mice and Rhesus Monkeys

Preexisting immunity to adenovirus serotype 5 (Ad5) has been shown to suppress the immunogenicity of recombinant Ad5 (rAd5) vector-based vaccines for human immunodeficiency virus type 1 (HIV-1) in both preclinical studies and clinical trials. A potential solution to this problem is to utilize rAd ve...

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Autori principali: Nanda, Anjali, Lynch, Diana M., Goudsmit, Jaap, Lemckert, Angelique A. C., Ewald, Bonnie A., Sumida, Shawn M., Truitt, Diana M., Abbink, Peter, Kishko, Michael G., Gorgone, Darci A., Lifton, Michelle A., Shen, Ling, Carville, Angela, Mansfield, Keith G., Havenga, Menzo J. E., Barouch, Dan H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280229/
https://ncbi.nlm.nih.gov/pubmed/16254351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14161-14168.2005
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