Immunogenicity of Recombinant Fiber-Chimeric Adenovirus Serotype 35 Vector-Based Vaccines in Mice and Rhesus Monkeys

Preexisting immunity to adenovirus serotype 5 (Ad5) has been shown to suppress the immunogenicity of recombinant Ad5 (rAd5) vector-based vaccines for human immunodeficiency virus type 1 (HIV-1) in both preclinical studies and clinical trials. A potential solution to this problem is to utilize rAd ve...

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Detalhes bibliográficos
Main Authors: Nanda, Anjali, Lynch, Diana M., Goudsmit, Jaap, Lemckert, Angelique A. C., Ewald, Bonnie A., Sumida, Shawn M., Truitt, Diana M., Abbink, Peter, Kishko, Michael G., Gorgone, Darci A., Lifton, Michelle A., Shen, Ling, Carville, Angela, Mansfield, Keith G., Havenga, Menzo J. E., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280229/
https://ncbi.nlm.nih.gov/pubmed/16254351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14161-14168.2005
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