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Mucosal Trafficking of Vector-Specific CD4(+) T Lymphocytes following Vaccination of Rhesus Monkeys with Adenovirus Serotype 5
Post hoc analysis of the phase 2b Step study evaluating a recombinant adenovirus serotype 5 (rAd5)-based HIV-1 vaccine candidate suggested a potential increased risk of HIV-1 acquisition in subjects who were baseline Ad5 seropositive and uncircumcised. These concerns had a profound impact on the HIV...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937774/ https://ncbi.nlm.nih.gov/pubmed/20686023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01157-10 |
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