Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol

BACKGROUND: Taxol is one of the most effective chemotherapeutic agents for the treatment of patients with breast cancer. Despite impressive clinical responses initially, the majority of patients eventually develop resistance to Taxol. Lactate dehydrogenase-A (LDH-A) is one of the predominant isoform...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhou, Ming, Zhao, Yuhua, Ding, Yan, Liu, Hao, Liu, Zixing, Fodstad, Oystein, Riker, Adam I, Kamarajugadda, Sushama, Lu, Jianrong, Owen, Laurie B, Ledoux, Susan P, Tan, Ming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829492/
https://ncbi.nlm.nih.gov/pubmed/20144215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-33
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