MicroRNA-125b Confers the Resistance of Breast Cancer Cells to Paclitaxel through Suppression of Pro-apoptotic Bcl-2 Antagonist Killer 1 (Bak1) Expression

Paclitaxel (Taxol) is an effective chemotherapeutic agent for treatment of cancer patients. Despite impressive initial clinical responses, the majority of patients eventually develop some degree of resistance to Taxol-based therapy. The mechanisms underlying cancer cells resistance to Taxol are not...

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Bibliografiske detaljer
Main Authors: Zhou, Ming, Liu, Zixing, Zhao, Yuhua, Ding, Yan, Liu, Hao, Xi, Yaguang, Xiong, Wei, Li, Guiyuan, Lu, Jianrong, Fodstad, Oystein, Riker, Adam I., Tan, Ming
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898411/
https://ncbi.nlm.nih.gov/pubmed/20460378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.083337
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