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Downregulation of microRNA-125a is involved in intervertebral disc degeneration by targeting pro-apoptotic Bcl-2 antagonist killer 1

OBJECTIVE(S): To investigate the role of the microRNA-125a (miR-125a) and BAK1 in intervertebral disc degeneration (IDD). MATERIALS AND METHODS: Degenerative lumbar nucleus pulposus (NP) tissues were obtained from 193 patients who underwent resection, and normal controls consisted of normal NP tissu...

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Pubblicato in:Iran J Basic Med Sci
Autori principali: Liu, Ping, Chang, Feng, Zhang, Ting, Gao, Gang, Yu, Chen, Ding, Sheng-Qiang, Zuo, Gen-Le, Huang, Xin-Hu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mashhad University of Medical Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749361/
https://ncbi.nlm.nih.gov/pubmed/29299204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2017.9542
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