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Suppression of lactate dehydrogenase A compromises tumor progression by downregulation of the Warburg effect in glioblastoma
Reprogrammed glucose metabolism is an emerging hallmark of cancer cells, which show a unique metabolic phenotype known as the Warburg effect. Lactate dehydrogenase A (LDHA), a key enzyme in the glycolytic process, executes the final step by conversion of lactate into pyruvate. However, little is kno...
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| Publicado no: | Neuroreport |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4712768/ https://ncbi.nlm.nih.gov/pubmed/26694942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000506 |
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