Mitochondrial Gene Therapy Augments Mitochondrial Physiology in a Parkinson's Disease Cell Model

Neurodegeneration in Parkinson's disease (PD) affects mainly dopaminergic neurons in the substantia nigra, where age-related, increasing percentages of cells lose detectable respiratory activity associated with depletion of intact mitochondrial DNA (mtDNA). Replenishment of mtDNA might improve...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Keeney, Paula M., Quigley, Caitlin K., Dunham, Lisa D., Papageorge, Christina M., Iyer, Shilpa, Thomas, Ravindar R., Schwarz, Kathleen M., Trimmer, Patricia A., Khan, Shaharyar M., Portell, Francisco R., Bergquist, Kristen E., Bennett, James P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2009
Schlagworte:
Scientific Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829286/
https://ncbi.nlm.nih.gov/pubmed/19374590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.023
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge