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Mitochondrial quality, dynamics and functional capacity in Parkinson’s disease cybrid cell lines selected for Lewy body expression

BACKGROUND: Lewy bodies (LB) are a neuropathological hallmark of Parkinson’s disease (PD) and other synucleinopathies. The role their formation plays in disease pathogenesis is not well understood, in part because studies of LB have been limited to examination of post-mortem tissue. LB formation may...

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Detalhes bibliográficos
Main Authors: Cronin-Furman, Emily N, Borland, M Kathleen, Bergquist, Kristen E, Bennett, James P, Trimmer, Patricia A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577453/
https://ncbi.nlm.nih.gov/pubmed/23351342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-6
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