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Cybrid Models of Parkinson's Disease Show Variable Mitochondrial Biogenesis and Genotype-Respiration Relationships

Sporadic Parkinson's disease (sPD) is a nervous system-wide disease that presents with a bradykinetic movement disorder and frequently progresses to include depression and cognitive impairment. Cybrid models of sPD are based on expression of sPD platelet mitochondrial DNA (mtDNA) in neural cell...

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Detalhes bibliográficos
Main Authors: Keeney, Paula M., Dunham, Lisa D., Quigley, Caitlin K., Morton, Stephanie L., Bergquist, Kristen E., Bennett, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783275/
https://ncbi.nlm.nih.gov/pubmed/19815014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.09.025
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