Recombinant Mitochondrial Transcription Factor A with N-terminal Mitochondrial Transduction Domain Increases Respiration and Mitochondrial Gene Expression

We developed a scalable procedure to produce human mitochondrial transcription factor A (TFAM) modified with an N-terminal protein transduction domain (PTD) and mitochondrial localization signal (MLS) that allow it to cross membranes and enter mitochondria through its “mitochondrial transduction dom...

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Main Authors: Iyer, Shilpa, Thomas, Ravindar R., Portell, Francisco R., Dunham, Lisa D., Quigley, Caitlin K., Bennett, James P.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783715/
https://ncbi.nlm.nih.gov/pubmed/19460293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2009.01.012
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