ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions

Por Bennett James P, Keeney Paula M
Publicado em 2010-05-01

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions

Por Keeney, Paula M, Bennett, James P
Publicado em 2010

Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux

Por O'Brien, Laura C., Keeney, Paula M., Bennett, James P.
Publicado no Stem Cells Dev (2015)

Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mt...

Por Arthur, Charles R, Morton, Stephanie L, Dunham, Lisa D, Keeney, Paula M, Bennett, James P
Publicado em 2009

Cybrid Models of Parkinson's Disease Show Variable Mitochondrial Biogenesis and Genotype-Respiration Relationships

Por Keeney, Paula M., Dunham, Lisa D., Quigley, Caitlin K., Morton, Stephanie L., Bergquist, Kristen E., Bennett, James P.
Publicado em 2009

Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cell...

Por Borland, M Kathleen, Trimmer, Patricia A, Rubinstein, Jeremy D, Keeney, Paula M, Mohanakumar, KP, Liu, Lei, Bennett, James P
Publicado em 2008

Relationships Among Molecular Genetic and Respiratory Properties of Parkinson’s Disease Cybrid Cells Show Similarities to Parkinson’s Brain Tissues

Por Borland, M. Kathleen, Mohanakumar, K. P., Rubinstein, Jeremy D., Keeney, Paula M., Xie, Jing, Capaldi, Roderick, Dunham, Lisa D., Trimmer, Patricia A., Bennett, James P.
Publicado em 2008

Mitochondrial Gene Therapy Augments Mitochondrial Physiology in a Parkinson's Disease Cell Model

Por Keeney, Paula M., Quigley, Caitlin K., Dunham, Lisa D., Papageorge, Christina M., Iyer, Shilpa, Thomas, Ravindar R., Schwarz, Kathleen M., Trimmer, Patricia A., Khan, Shaharyar M., Portell, Francisco R., Bergquist, Kristen E., Bennett, James P.
Publicado em 2009