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Mitochondrial quality, dynamics and functional capacity in Parkinson’s disease cybrid cell lines selected for Lewy body expression

BACKGROUND: Lewy bodies (LB) are a neuropathological hallmark of Parkinson’s disease (PD) and other synucleinopathies. The role their formation plays in disease pathogenesis is not well understood, in part because studies of LB have been limited to examination of post-mortem tissue. LB formation may...

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Autors principals: Cronin-Furman, Emily N, Borland, M Kathleen, Bergquist, Kristen E, Bennett, James P, Trimmer, Patricia A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577453/
https://ncbi.nlm.nih.gov/pubmed/23351342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-6
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