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PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

Protein tyrosine phosphatase 1B (PTP1B) and SH2 domain–containing protein tyrosine phosphatase–2 (SHP2) have been shown in mice to regulate metabolism via the central nervous system, but the specific neurons mediating these effects are unknown. Here, we have shown that proopiomelanocortin (POMC) neu...

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Detalhes bibliográficos
Main Authors: Banno, Ryoichi, Zimmer, Derek, De Jonghe, Bart C., Atienza, Marybless, Rak, Kimberly, Yang, Wentian, Bence, Kendra K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827947/
https://ncbi.nlm.nih.gov/pubmed/20160350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39620
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