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PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

Protein tyrosine phosphatase 1B (PTP1B) and SH2 domain–containing protein tyrosine phosphatase–2 (SHP2) have been shown in mice to regulate metabolism via the central nervous system, but the specific neurons mediating these effects are unknown. Here, we have shown that proopiomelanocortin (POMC) neu...

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書誌詳細
主要な著者: Banno, Ryoichi, Zimmer, Derek, De Jonghe, Bart C., Atienza, Marybless, Rak, Kimberly, Yang, Wentian, Bence, Kendra K.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827947/
https://ncbi.nlm.nih.gov/pubmed/20160350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39620
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