Ablation of intact hypothalamic and/or hindbrain TrkB signaling leads to perturbations in energy balance

OBJECTIVE: Brain-derived neurotrophic factor (BDNF) and its receptor, tropomyosin receptor kinase B (TrkB), play a paramount role in the central regulation of energy balance. Despite the substantial body of genetic evidence implicating BDNF- or TrkB-deficiency in human obesity, the critical brain re...

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Publicado en:Mol Metab
Main Authors: Ozek, Ceren, Zimmer, Derek J., De Jonghe, Bart C., Kalb, Robert G., Bence, Kendra K.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
Assuntos:
Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632115/
https://ncbi.nlm.nih.gov/pubmed/26629410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.08.002
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