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Protein-tyrosine Phosphatase 1B (PTP1B) Is a Novel Regulator of Central Brain-derived Neurotrophic Factor and Tropomyosin Receptor Kinase B (TrkB) Signaling

Neuronal protein-tyrosine phosphatase 1B (PTP1B) deficiency in mice results in enhanced leptin signaling and protection from diet-induced obesity; however, whether additional signaling pathways in the brain contribute to the metabolic effects of PTP1B deficiency remains unclear. Here, we show that t...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Ozek, Ceren, Kanoski, Scott E., Zhang, Zhong-Yin, Grill, Harvey J., Bence, Kendra K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231649/
https://ncbi.nlm.nih.gov/pubmed/25288805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603621
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