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TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits

The TrkB receptor is critical for the control of energy balance, as mutations in its gene (NTRK2) lead to hyperphagia and severe obesity. The main neural substrate mediating the appetite-suppressing activity of TrkB, however, remains unknown. Here, we demonstrate that selective Ntrk2 deletion within...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: An, Juan Ji, Kinney, Clint E., Tan, Ji-Wei, Liao, Guey-Ying, Kremer, Eric J., Xu, Baoji
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138837/
https://ncbi.nlm.nih.gov/pubmed/32265438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15537-w
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