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PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice
Protein tyrosine phosphatase 1B (PTP1B) and SH2 domain–containing protein tyrosine phosphatase–2 (SHP2) have been shown in mice to regulate metabolism via the central nervous system, but the specific neurons mediating these effects are unknown. Here, we have shown that proopiomelanocortin (POMC) neu...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827947/ https://ncbi.nlm.nih.gov/pubmed/20160350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39620 |
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