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Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα

MutLα, the heterodimeric eukaryotic MutL homolog, is required for DNA mismatch repair (MMR) in vivo. It has been suggested that conformational changes, modulated by adenine nucleotides, mediate the interactions of MutLα with other proteins in the MMR pathway, coordinating the recognition of DNA mism...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sacho, Elizabeth J, Kadyrov, Farid A, Modrich, Paul, Kunkel, Thomas A, Erie, Dorothy A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820111/
https://ncbi.nlm.nih.gov/pubmed/18206974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.10.030
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