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Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα
MutLα, the heterodimeric eukaryotic MutL homolog, is required for DNA mismatch repair (MMR) in vivo. It has been suggested that conformational changes, modulated by adenine nucleotides, mediate the interactions of MutLα with other proteins in the MMR pathway, coordinating the recognition of DNA mism...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820111/ https://ncbi.nlm.nih.gov/pubmed/18206974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.10.030 |
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