Dynamic human MutSα–MutLα complexes compact mismatched DNA

DNA mismatch repair (MMR) corrects errors that occur during DNA replication. In humans, mutations in the proteins MutSα and MutLα that initiate MMR cause Lynch syndrome, the most common hereditary cancer. MutSα surveilles the DNA, and upon recognition of a replication error it undergoes adenosine tr...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Bradford, Kira C., Wilkins, Hunter, Hao, Pengyu, Li, Zimeng M., Wang, Bangchen, Burke, Dan, Wu, Dong, Smith, Austin E., Spaller, Logan, Du, Chunwei, Gauer, Jacob W., Chan, Edward, Hsieh, Peggy, Weninger, Keith R., Erie, Dorothy A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2020
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368325/
https://ncbi.nlm.nih.gov/pubmed/32586954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918519117
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