Dynamic human MutSα–MutLα complexes compact mismatched DNA

DNA mismatch repair (MMR) corrects errors that occur during DNA replication. In humans, mutations in the proteins MutSα and MutLα that initiate MMR cause Lynch syndrome, the most common hereditary cancer. MutSα surveilles the DNA, and upon recognition of a replication error it undergoes adenosine tr...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Bradford, Kira C., Wilkins, Hunter, Hao, Pengyu, Li, Zimeng M., Wang, Bangchen, Burke, Dan, Wu, Dong, Smith, Austin E., Spaller, Logan, Du, Chunwei, Gauer, Jacob W., Chan, Edward, Hsieh, Peggy, Weninger, Keith R., Erie, Dorothy A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368325/
https://ncbi.nlm.nih.gov/pubmed/32586954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918519117
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