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Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

MutS homologs identify base-pairing errors made in DNA during replication and initiate their repair. In the presence of adenosine triphosphate, MutS induces DNA bending upon mismatch recognition and subsequently undergoes conformational transitions that promote its interaction with MutL to signal re...

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Foilsithe in:Nucleic Acids Res
Main Authors: LeBlanc, Sharonda J, Gauer, Jacob W, Hao, Pengyu, Case, Brandon C, Hingorani, Manju M, Weninger, Keith R, Erie, Dorothy A
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237781/
https://ncbi.nlm.nih.gov/pubmed/30272207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky865
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