Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

MutS homologs identify base-pairing errors made in DNA during replication and initiate their repair. In the presence of adenosine triphosphate, MutS induces DNA bending upon mismatch recognition and subsequently undergoes conformational transitions that promote its interaction with MutL to signal re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: LeBlanc, Sharonda J, Gauer, Jacob W, Hao, Pengyu, Case, Brandon C, Hingorani, Manju M, Weninger, Keith R, Erie, Dorothy A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Genome Integrity, Repair and Replication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237781/
https://ncbi.nlm.nih.gov/pubmed/30272207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky865
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