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Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

MutS homologs identify base-pairing errors made in DNA during replication and initiate their repair. In the presence of adenosine triphosphate, MutS induces DNA bending upon mismatch recognition and subsequently undergoes conformational transitions that promote its interaction with MutL to signal re...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: LeBlanc, Sharonda J, Gauer, Jacob W, Hao, Pengyu, Case, Brandon C, Hingorani, Manju M, Weninger, Keith R, Erie, Dorothy A
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237781/
https://ncbi.nlm.nih.gov/pubmed/30272207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky865
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