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Mechanism of MutS Searching for DNA Mismatches and Signaling Repair

DNA mismatch repair is initiated by the recognition of mismatches by MutS proteins. The mechanism by which MutS searches for and recognizes mismatches and subsequently signals repair remains poorly understood. We used single-molecule analyses of atomic force microscopy images of MutS-DNA complexes,...

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Detalhes bibliográficos
Main Authors: Tessmer, Ingrid, Yang, Yong, Zhai, Jie, Du, Chungwei, Hsieh, Peggy, Hingorani, Manju M., Erie, Dorothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606009/
https://ncbi.nlm.nih.gov/pubmed/18854319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805712200
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