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The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair
We have examined the interaction parameters, conformation, and functional significance of the human MutSα(·) proliferating cell nuclear antigen (PCNA) complex in mismatch repair. The two proteins associate with a 1:1 stoichiometry and a K(D) of 0.7 μm in the absence or presence of heteroduplex DNA....
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423938/ https://ncbi.nlm.nih.gov/pubmed/18326858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800606200 |
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