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The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair
We have examined the interaction parameters, conformation, and functional significance of the human MutSα(·) proliferating cell nuclear antigen (PCNA) complex in mismatch repair. The two proteins associate with a 1:1 stoichiometry and a K(D) of 0.7 μm in the absence or presence of heteroduplex DNA....
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423938/ https://ncbi.nlm.nih.gov/pubmed/18326858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800606200 |
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