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The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair

We have examined the interaction parameters, conformation, and functional significance of the human MutSα(·) proliferating cell nuclear antigen (PCNA) complex in mismatch repair. The two proteins associate with a 1:1 stoichiometry and a K(D) of 0.7 μm in the absence or presence of heteroduplex DNA....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Iyer, Ravi R., Pohlhaus, Timothy J., Chen, Sihong, Hura, Gregory L., Dzantiev, Leonid, Beese, Lorena S., Modrich, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423938/
https://ncbi.nlm.nih.gov/pubmed/18326858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800606200
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