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Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair

A purified system comprised of MutSα, MutLα, exonuclease 1 (Exo1), and replication protein A (RPA) (in the absence or presence of HMGB1) supports 5′-directed mismatch-provoked excision that terminates after mismatch removal. MutLα is not essential for this reaction but enhances excision termination,...

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Bibliografski detalji
Glavni autori: Genschel, Jochen, Modrich, Paul
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755878/
https://ncbi.nlm.nih.gov/pubmed/19515846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021287
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