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Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair

A purified system comprised of MutSα, MutLα, exonuclease 1 (Exo1), and replication protein A (RPA) (in the absence or presence of HMGB1) supports 5′-directed mismatch-provoked excision that terminates after mismatch removal. MutLα is not essential for this reaction but enhances excision termination,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Genschel, Jochen, Modrich, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755878/
https://ncbi.nlm.nih.gov/pubmed/19515846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021287
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