Dynamic human MutSα–MutLα complexes compact mismatched DNA

DNA mismatch repair (MMR) corrects errors that occur during DNA replication. In humans, mutations in the proteins MutSα and MutLα that initiate MMR cause Lynch syndrome, the most common hereditary cancer. MutSα surveilles the DNA, and upon recognition of a replication error it undergoes adenosine tr...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Bradford, Kira C., Wilkins, Hunter, Hao, Pengyu, Li, Zimeng M., Wang, Bangchen, Burke, Dan, Wu, Dong, Smith, Austin E., Spaller, Logan, Du, Chunwei, Gauer, Jacob W., Chan, Edward, Hsieh, Peggy, Weninger, Keith R., Erie, Dorothy A.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2020
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368325/
https://ncbi.nlm.nih.gov/pubmed/32586954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918519117
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料