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Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα

MutLα, the heterodimeric eukaryotic MutL homolog, is required for DNA mismatch repair (MMR) in vivo. It has been suggested that conformational changes, modulated by adenine nucleotides, mediate the interactions of MutLα with other proteins in the MMR pathway, coordinating the recognition of DNA mism...

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Bibliografische gegevens
Hoofdauteurs: Sacho, Elizabeth J, Kadyrov, Farid A, Modrich, Paul, Kunkel, Thomas A, Erie, Dorothy A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820111/
https://ncbi.nlm.nih.gov/pubmed/18206974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.10.030
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