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Endonuclease activities of MutLα and its homologs in DNA mismatch repair
MutLα is a key component of the DNA mismatch repair system in eukaryotes. The DNA mismatch repair system has several genetic stabilization functions. Of these functions, DNA mismatch repair is the major one. The loss of MutLα abolishes DNA mismatch repair, thereby predisposing humans to cancer. MutL...
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| Yayımlandı: | DNA Repair (Amst) |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820397/ https://ncbi.nlm.nih.gov/pubmed/26719141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.11.023 |
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