Buffer Optimization of Thermal Melt Assays of Plasmodium Proteins for Detection of Small-Molecule Ligands

In the last decade, thermal melt/thermal shift assays have become a common tool for identifying ligands and other factors that stabilize specific proteins. Increased stability is indicated by an increase in the protein's melting temperature (T(m)). In optimizing the assays for subsequent screen...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Crowther, Gregory J., Napuli, Alberto J., Thomas, Andrew P., Chung, Diana J., Kovzun, Kuzma V., Leibly, David J., Castaneda, Lisa J., Bhandari, Janhavi, Damman, Christopher J., Hui, Raymond, Hol, Wim G. J., Buckner, Frederick S., Verlinde, Christophe L. M. J., Zhang, Zhongsheng, Fan, Erkang, Van Voorhis, Wesley C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819745/
https://ncbi.nlm.nih.gov/pubmed/19470714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057109335749
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky