Selective Inhibitors of Methionyl-tRNA Synthetase Have Potent Activity against Trypanosoma brucei Infection in Mice

Human African trypanosomiasis continues to be an important public health threat in extensive regions of sub-Saharan Africa. Treatment options for infected patients are unsatisfactory due to toxicity, difficult administration regimes, and poor efficacy of available drugs. The aminoacyl-tRNA synthetas...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Shibata, Sayaka, Gillespie, J. Robert, Kelley, Angela M., Napuli, Alberto J., Zhang, Zhongsheng, Kovzun, Kuzma V., Pefley, Ranae M., Lam, Jocelyn, Zucker, Frank H., Van Voorhis, Wesley C., Merritt, Ethan A., Hol, Wim G. J., Verlinde, Christophe L. M. J., Fan, Erkang, Buckner, Frederick S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2011
विषय:
Experimental Therapeutics
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088252/
https://ncbi.nlm.nih.gov/pubmed/21282428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01796-10
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