Selective Inhibitors of Methionyl-tRNA Synthetase Have Potent Activity against Trypanosoma brucei Infection in Mice

Human African trypanosomiasis continues to be an important public health threat in extensive regions of sub-Saharan Africa. Treatment options for infected patients are unsatisfactory due to toxicity, difficult administration regimes, and poor efficacy of available drugs. The aminoacyl-tRNA synthetas...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Shibata, Sayaka, Gillespie, J. Robert, Kelley, Angela M., Napuli, Alberto J., Zhang, Zhongsheng, Kovzun, Kuzma V., Pefley, Ranae M., Lam, Jocelyn, Zucker, Frank H., Van Voorhis, Wesley C., Merritt, Ethan A., Hol, Wim G. J., Verlinde, Christophe L. M. J., Fan, Erkang, Buckner, Frederick S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2011
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088252/
https://ncbi.nlm.nih.gov/pubmed/21282428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01796-10
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items