Selective Inhibitors of Methionyl-tRNA Synthetase Have Potent Activity against Trypanosoma brucei Infection in Mice

Human African trypanosomiasis continues to be an important public health threat in extensive regions of sub-Saharan Africa. Treatment options for infected patients are unsatisfactory due to toxicity, difficult administration regimes, and poor efficacy of available drugs. The aminoacyl-tRNA synthetas...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Shibata, Sayaka, Gillespie, J. Robert, Kelley, Angela M., Napuli, Alberto J., Zhang, Zhongsheng, Kovzun, Kuzma V., Pefley, Ranae M., Lam, Jocelyn, Zucker, Frank H., Van Voorhis, Wesley C., Merritt, Ethan A., Hol, Wim G. J., Verlinde, Christophe L. M. J., Fan, Erkang, Buckner, Frederick S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088252/
https://ncbi.nlm.nih.gov/pubmed/21282428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01796-10
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky