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Resistance to IFN-alpha-induced apoptosis is linked to a loss of STAT2
Type I interferons (IFN-α/β) are pleitropic cytokines widely used in the treatment of certain malignancies, hepatitis B and C and multiple sclerosis. IFN resistance is a challenging clinical problem to overcome. Hence understanding the molecular mechanism by which IFN immunotherapy ceases to be effe...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808460/ https://ncbi.nlm.nih.gov/pubmed/20068068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0344 |
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