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Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response

Serine phosphorylation of STAT proteins is an important post-translational modification event that, in addition to tyrosine phosphorylation, is required for strong transcriptional activity. However, we recently showed that phosphorylation of STAT2 on S287 induced by type I interferons (IFN-α and IFN...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Steen, Håkan C., Kotredes, Kevin P., Nogusa, Shoko, Harris, Michele Y., Balachandran, Siddharth, Gamero, Ana M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518330/
https://ncbi.nlm.nih.gov/pubmed/27802159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.185421
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