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Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1
In response to viral infection, the host induces over 300 IFN-stimulated genes (ISGs), which are the central component of intracellular antiviral innate immunity. Inefficient induction of ISGs contributes to poor control and persistence of hepatitis C virus infection. Therefore, further understandin...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918791/ https://ncbi.nlm.nih.gov/pubmed/24449862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314268111 |
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