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Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1

In response to viral infection, the host induces over 300 IFN-stimulated genes (ISGs), which are the central component of intracellular antiviral innate immunity. Inefficient induction of ISGs contributes to poor control and persistence of hepatitis C virus infection. Therefore, further understandin...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ooi, Ee Lyn, Chan, Stephanie T., Cho, Noell E., Wilkins, Courtney, Woodward, Jessica, Li, Meng, Kikkawa, Ushio, Tellinghuisen, Timothy, Gale, Michael, Saito, Takeshi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918791/
https://ncbi.nlm.nih.gov/pubmed/24449862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314268111
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