Inhibition of PI3K by PX-866 Prevents Transforming Growth Factor-α–Induced Pulmonary Fibrosis

Transforming growth factor-α (TGFα) is a ligand for the epidermal growth factor receptor (EGFR). EGFR activation is associated with fibroproliferative processes in human lung disease and animal models of pulmonary fibrosis. EGFR signaling activates several intracellular signaling pathways including...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Le Cras, Timothy D., Korfhagen, Thomas R., Davidson, Cynthia, Schmidt, Stephanie, Fenchel, Matthew, Ikegami, Machiko, Whitsett, Jeffrey A., Hardie, William D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2010
Aiheet:
Regular Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808075/
https://ncbi.nlm.nih.gov/pubmed/20042669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090123
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