Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase–dependent manner

Nitrite (NO(2)(−)), previously viewed as a physiologically inert metabolite and biomarker of the endogenous vasodilator NO, was recently identified as an important biological NO reservoir in vasculature and tissues, where it contributes to hypoxic signaling, vasodilation, and cytoprotection after is...

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Bibliografiske detaljer
Main Authors: Cauwels, Anje, Buys, Emmanuel S., Thoonen, Robrecht, Geary, Lisa, Delanghe, Joris, Shiva, Sruti, Brouckaert, Peter
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2009
Fag:
Brief Definitive Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806477/
https://ncbi.nlm.nih.gov/pubmed/19934018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091236
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