The Soluble Guanylate Cyclase Activator BAY 58-2667 Protects against Morbidity and Mortality in Endotoxic Shock by Recoupling Organ Systems

Sepsis and septic shock are associated with high mortality rates and the majority of sepsis patients die due to complications of multiple organ failure (MOF). The cyclic GMP (cGMP) producing enzyme soluble guanylate cyclase (sGC) is crucially involved in the regulation of (micro)vascular homeostasis...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Vandendriessche, Benjamin, Rogge, Elke, Goossens, Vera, Vandenabeele, Peter, Stasch, Johannes-Peter, Brouckaert, Peter, Cauwels, Anje
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756074/
https://ncbi.nlm.nih.gov/pubmed/24015214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072155
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