The Soluble Guanylate Cyclase Activator BAY 58-2667 Protects against Morbidity and Mortality in Endotoxic Shock by Recoupling Organ Systems

Sepsis and septic shock are associated with high mortality rates and the majority of sepsis patients die due to complications of multiple organ failure (MOF). The cyclic GMP (cGMP) producing enzyme soluble guanylate cyclase (sGC) is crucially involved in the regulation of (micro)vascular homeostasis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vandendriessche, Benjamin, Rogge, Elke, Goossens, Vera, Vandenabeele, Peter, Stasch, Johannes-Peter, Brouckaert, Peter, Cauwels, Anje
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756074/
https://ncbi.nlm.nih.gov/pubmed/24015214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072155
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