The Soluble Guanylyl Cyclase Activator Bay 58-2667 Selectively Limits Cardiomyocyte Hypertrophy

BACKGROUND: Although evidence now suggests cGMP is a negative regulator of cardiac hypertrophy, the direct consequences of the soluble guanylyl cyclase (sGC) activator BAY 58-2667 on cardiac remodeling, independent of changes in hemodynamic load, has not been investigated. In the present study, we t...

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Détails bibliographiques
Auteurs principaux: Irvine, Jennifer C., Ganthavee, Virat, Love, Jane E., Alexander, Amy E., Horowitz, John D., Stasch, Johannes-Peter, Kemp-Harper, Barbara K., Ritchie, Rebecca H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492396/
https://ncbi.nlm.nih.gov/pubmed/23144773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044481
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