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Heme deficiency of soluble guanylate cyclase induces gastroparesis
BACKGROUND: Soluble guanylate cyclase (sGC) is the principal target of nitric oxide (NO) to control gastrointestinal motility. The consequence on nitrergic signaling and gut motility of inducing a heme-free status of sGC, as induced by oxidative stress, was investigated. METHODS: sGCβ(1)(H105F) knoc...
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| Izdano u: | Neurogastroenterol Motil |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932850/ https://ncbi.nlm.nih.gov/pubmed/23551931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.12120 |
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