Pathophysiology of Hypertension in the Absence of Nitric Oxide/Cyclic GMP Signaling

Por Thoonen, Robrecht, Sips, Patrick Y., Bloch, Kenneth D., Buys, Emmanuel S.
Publicado em 2013

In vitro and in vivo studies on the importance of the soluble gyanylyl cyclase alpha 1 subunit in penile erection

Por Decaluwé, Kelly, Nimmegeers, Sofie, Thoonen, Robrecht, Brouckaert, Peter, Voorde, Johan Van de
Publicado em 2009

Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase–dependent manner

Por Cauwels, Anje, Buys, Emmanuel S., Thoonen, Robrecht, Geary, Lisa, Delanghe, Joris, Shiva, Sruti, Brouckaert, Peter
Publicado em 2009

Study on the involvement of soluble guanylyl cyclase and its different isoforms in carbon monoxide and carbon monoxide releasing molecule-2 induced vasodilatation

Por Decaluwé, Kelly, Pauwels, Bart, Verpoest, Sara, Thoonen, Robrecht, Buys, Emmanuel, Brouckaert, Peter, Van de Voorde, Johan
Publicado em 2011

Smooth muscle cell specific deletion of the PKGIα target RGS2 induces vascular dysfunction and hypertension

Por Thoonen, Robrecht, Zhang, Haihua, Abe, Yuichi, Nickerson, Heather, Aronovitz, Mark, Chambon, Pierre, Karas, Richard H, Mendelsohn, Michael E
Publicado em 2011

Mutation of the Protein Kinase I Alpha Leucine Zipper Domain Produces Hypertension and Progressive Left Ventricular Hypertrophy: A Novel Mouse Model of Age-Dependent Hypertensive H...

Por Blanton, Robert M., Takimoto, Eiki, Aronovitz, Mark, Thoonen, Robrecht, Kass, David A., Karas, Richard H., Mendelsohn, Michael E.
Publicado em 2013

Identification of protein kinase G I alpha interacting proteins as potential targets to prevent cardiac remodeling

Por Blanton, Robert, Lane, Angela, Aronovitz, Mark, Wang, Guang-Rong, Thoonen, Robrecht, Davis, Roger, Mendelsohn, Michael, Kass, David, Karas, Richard
Publicado em 2013

NO-insensitive sGCbeta1 H105F knockin mice: if NO has no place to go

Por Thoonen, Robrecht, Buys, Emmanuel, Cauwels, Anje, Rogge, Elke, Nimmegeers, Sofie, Hemel, Maureen Van den, Hochepied, Tino, Voorde, Johan Van de, Stasch, Johannes-Peter, Brouckaert, Peter
Publicado em 2009

A Molecular Screen Identifies Cardiac Myosin Binding Protein-C as a Protein Kinase G I Alpha Substrate

Por Thoonen, Robrecht, Giovanni, Shewit, Govindan, Suresh, Lee, Dong I., Wang, Guang-rong, Calamaras, Timothy D., Takimoto, Eiki, Kass, David A., Sadayappan, Sakthivel, Blanton, Robert M.
Publicado no Circ Heart Fail (2015)

Relationship of brown adipose tissue perfusion and function: a study through β2-adrenoreceptor stimulation

Por Ernande, Laura, Stanford, Kristin I., Thoonen, Robrecht, Zhang, Haihua, Clerte, Maëva, Hirshman, Michael F., Goodyear, Laurie J., Bloch, Kenneth D., Buys, Emmanuel S., Scherrer-Crosbie, Marielle
Publicado no J Appl Physiol (1985) (2016)

Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome

Por Ferrari, Michele, Jain, Isha H., Goldberger, Olga, Rezoagli, Emanuele, Thoonen, Robrecht, Cheng, Kai-Hung, Sosnovik, David E., Scherrer-Crosbie, Marielle, Mootha, Vamsi K., Zapol, Warren M.
Publicado no Proc Natl Acad Sci U S A (2017)

Phenotypes of sGC mutant mice in basic conditions, disease and shock

Por Brouckaert, Peter, Cauwels, Anje, Thoonen, Robrecht, Buys, Emmanuel, Bloch, KD, Sips, Patrick, Ichinose, Fumito, Rogge, Elke, Nimmegeers, Sofie, Voorde, Johan Van de, Lefebvre, Romain, Stasch, Johannes-Peter
Publicado em 2009

Sensitivity to Sevoflurane anesthesia is decreased in mice with a congenital deletion of Guanylyl Cyclase-1 alpha

Por Nagasaka, Yasuko, Wepler, Martin, Thoonen, Robrecht, Sips, Patrick Y., Allen, Kaitlin, Graw, Jan A., Yao, Vincent, Burns, Sara M., Muenster, Stefan, Brouckaert, Peter, Miller, Keith, Solt, Ken, Buys, Emmanuel S., Ichinose, Fumito, Zapol, Warren M.
Publicado no BMC Anesthesiol (2017)

sGCα(1)β(1) attenuates cardiac dysfunction and mortality in murine inflammatory shock models

Por Buys, Emmanuel S., Cauwels, Anje, Raher, Michael J., Passeri, Jonathan J., Hobai, Ion, Cawley, Sharon M., Rauwerdink, Kristen M., Thibault, Helene, Sips, Patrick Y., Thoonen, Robrecht, Scherrer-Crosbie, Marielle, Ichinose, Fumito, Brouckaert, Peter, Bloch, Kenneth D.
Publicado em 2009

sGCα(1)β(1 )attenuates cardiac dysfunction and mortality in murine inflammatory shock models

Por Buys, Emmanuel S, Cauwels, Anje, Raher, Michael J, Passeri, Jonathan J, Hobai, Ion, Cawley, Sharon M, Rauwerdink, Kristen M, Thibault, Helene, Sips, Patrick Y, Thoonen, Robrecht, Scherrer-Crosbie, Marielle, Ichinose, Fumito, Brouckaert, Peter, Bloch, Kenneth D
Publicado em 2009

Functional brown adipose tissue limits cardiomyocyte injury and adverse remodeling in catecholamine-induced cardiomyopathy

Por Thoonen, Robrecht, Ernande, Laura, Cheng, Juan, Nagasaka, Yasuko, Yao, Vincent, Miranda-Bezerra, Alexandre, Chen, Chan, Chao, Wei, Panagia, Marcello, Sosnovik, David E., Puppala, Dheeraj, Armoundas, Antonis A., Hindle, Allyson, Bloch, Kenneth D., Buys, Emmanuel S., Scherrer-Crosbie, Marielle
Publicado no J Mol Cell Cardiol (2015)

BMP type I receptor ALK2 is required for angiotensin II-induced cardiac hypertrophy

Por Shahid, Mohd, Spagnolli, Ester, Ernande, Laura, Thoonen, Robrecht, Kolodziej, Starsha A., Leyton, Patricio A., Cheng, Juan, Tainsh, Robert E. T., Mayeur, Claire, Rhee, David K., Wu, Mei. X., Scherrer-Crosbie, Marielle, Buys, Emmanuel S., Zapol, Warren M., Bloch, Kenneth D., Bloch, Donald B.
Publicado no Am J Physiol Heart Circ Physiol (2016)

Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice

Por Thoonen, Robrecht, Cauwels, Anje, Decaluwe, Kelly, Geschka, Sandra, Tainsh, Robert E., Delanghe, Joris, Hochepied, Tino, De Cauwer, Lode, Rogge, Elke, Voet, Sofie, Sips, Patrick, Karas, Richard H., Bloch, Kenneth D., Vuylsteke, Marnik, Stasch, Johannes-Peter, Van de Voorde, Johan, Buys, Emmanuel S., Brouckaert, Peter
Publicado no Nat Commun (2015)

Androgen-sensitive hypertension associated with soluble guanylate cyclase alpha1 deficiency is mediated by 20-HETE

Por Vandenwijngaert, Sara, Dordea, Ana C, Garcia, Victor, Tainsh, Robert E, Nathan, Daniel I, Raher, Michael J, Allen, Kaitlin, Zhang, Fan, Lieb, Wolfgang S, Mikelman, Sarah, Kirby, Andrew, Stevens, Christine, Thoonen, Robrecht, Hindle, Allyson, Sips, Patrick Y, Malhotra, Rajeev, Daly, Mark J, Brouckaert, Peter, Bloch, Kenneth D, Schwartzman, Michal, Buys, Emmanuel S
Publicado no BMC Pharmacol Toxicol (2015)

Androgen-sensitive hypertension associated with soluble guanylate cyclase-α(1) deficiency is mediated by 20-HETE

Por Dordea, Ana C., Vandenwijngaert, Sara, Garcia, Victor, Tainsh, Robert E. T., Nathan, Daniel I., Allen, Kaitlin, Raher, Michael J., Tainsh, Laurel T., Zhang, Fan, Lieb, Wolfgang S., Mikelman, Sarah, Kirby, Andrew, Stevens, Christine, Thoonen, Robrecht, Hindle, Allyson G., Sips, Patrick Y., Falck, John R., Daly, Mark J., Brouckaert, Peter, Bloch, Kenneth D., Bloch, Donald B., Malhotra, Rajeev, Schwartzman, Michal L., Buys, Emmanuel S.
Publicado no Am J Physiol Heart Circ Physiol (2016)