Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase–dependent manner

Nitrite (NO(2)(−)), previously viewed as a physiologically inert metabolite and biomarker of the endogenous vasodilator NO, was recently identified as an important biological NO reservoir in vasculature and tissues, where it contributes to hypoxic signaling, vasodilation, and cytoprotection after is...

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Bibliographische Detailangaben
Hauptverfasser: Cauwels, Anje, Buys, Emmanuel S., Thoonen, Robrecht, Geary, Lisa, Delanghe, Joris, Shiva, Sruti, Brouckaert, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2009
Schlagworte:
Brief Definitive Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806477/
https://ncbi.nlm.nih.gov/pubmed/19934018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091236
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