Regulation of mTOR Complex 1 (mTORC1) by Raptor Ser(863) and Multisite Phosphorylation

The rapamycin-sensitive mTOR complex 1 (mTORC1) promotes protein synthesis, cell growth, and cell proliferation in response to growth factors and nutritional cues. To elucidate the poorly defined mechanisms underlying mTORC1 regulation, we have studied the phosphorylation of raptor, an mTOR-interact...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Foster, Kathryn G., Acosta-Jaquez, Hugo A., Romeo, Yves, Ekim, Bilgen, Soliman, Ghada A., Carriere, Audrey, Roux, Philippe P., Ballif, Bryan A., Fingar, Diane C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mechanisms of Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804229/
https://ncbi.nlm.nih.gov/pubmed/19864431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.029637
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