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mTOR Kinase Domain Phosphorylation Promotes mTORC1 Signaling, Cell Growth, and Cell Cycle Progression

The mammalian target of rapamycin complex 1 (mTORC1) functions as an environmental sensor to promote critical cellular processes such as protein synthesis, cell growth, and cell proliferation in response to growth factors and nutrients. While diverse stimuli regulate mTORC1 signaling, the direct mol...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ekim, Bilgen, Magnuson, Brian, Acosta-Jaquez, Hugo A., Keller, Jennifer A., Feener, Edward P., Fingar, Diane C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133410/
https://ncbi.nlm.nih.gov/pubmed/21576368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05437-11
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