ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)

The Ras/mitogen-activated protein kinase (MAPK) pathway regulates a variety of cellular processes by activating specific transcriptional and translational programs. Ras/MAPK signaling promotes mRNA translation and protein synthesis, but the exact molecular mechanisms underlying this regulation remai...

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Detalhes bibliográficos
Main Authors: Carriere, Audrey, Romeo, Yves, Acosta-Jaquez, Hugo A., Moreau, Julie, Bonneil, Eric, Thibault, Pierre, Fingar, Diane C., Roux, Philippe P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013016/
https://ncbi.nlm.nih.gov/pubmed/21071439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.159046
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