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mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling

The mammalian target of rapamycin (mTOR) is a conserved Ser/Thr kinase that forms two functionally distinct complexes important for nutrient and growth factor signaling. While mTOR complex 1 (mTORC1) regulates mRNA translation and ribosome biogenesis, mTORC2 plays an important role in the phosphoryl...

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Bibliografiske detaljer
Main Authors: Julien, Louis-Andre, Carriere, Audrey, Moreau, Julie, Roux, Philippe P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815569/
https://ncbi.nlm.nih.gov/pubmed/19995915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00601-09
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