Site-Specific mTOR Phosphorylation Promotes mTORC1-Mediated Signaling and Cell Growth

The mammalian target of rapamycin (mTOR) complex 1 (mTORC1) functions as a rapamycin-sensitive environmental sensor that promotes cellular biosynthetic processes in response to growth factors and nutrients. While diverse physiological stimuli modulate mTORC1 signaling, the direct biochemical mechani...

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Main Authors: Acosta-Jaquez, Hugo A., Keller, Jennifer A., Foster, Kathryn G., Ekim, Bilgen, Soliman, Ghada A., Feener, Edward P., Ballif, Bryan A., Fingar, Diane C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715808/
https://ncbi.nlm.nih.gov/pubmed/19487463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01665-08
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