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Site-Specific mTOR Phosphorylation Promotes mTORC1-Mediated Signaling and Cell Growth
The mammalian target of rapamycin (mTOR) complex 1 (mTORC1) functions as a rapamycin-sensitive environmental sensor that promotes cellular biosynthetic processes in response to growth factors and nutrients. While diverse physiological stimuli modulate mTORC1 signaling, the direct biochemical mechani...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715808/ https://ncbi.nlm.nih.gov/pubmed/19487463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01665-08 |
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