Misfolded Proinsulin Affects Bystander Proinsulin in Neonatal Diabetes

It has previously been shown that misfolded mutant Akita proinsulin in the endoplasmic reticulum engages directly in protein complexes either with nonmutant proinsulin or with “hProCpepGFP” (human proinsulin bearing emerald-GFP within the C-peptide), impairing the trafficking of these “bystander” pr...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Hodish, Israel, Liu, Ming, Rajpal, Gautam, Larkin, Dennis, Holz, Ronald W., Adams, Aaron, Liu, Leanza, Arvan, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804216/
https://ncbi.nlm.nih.gov/pubmed/19880509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038042
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars