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Proinsulin misfolding and diabetes: Mutant INS gene-induced Diabetes of Youth
Type 1B diabetes (typically early onset; without islet autoantibodies) has been described in patients bearing small coding sequence mutations in the INS gene. Not all mutations in the INS gene cause the autosomal dominant Mutant INS-gene-induced Diabetes of Youth (MIDY) syndrome, but most missense m...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967602/ https://ncbi.nlm.nih.gov/pubmed/20724178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2010.07.001 |
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