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Proinsulin misfolding and diabetes: Mutant INS gene-induced Diabetes of Youth

Type 1B diabetes (typically early onset; without islet autoantibodies) has been described in patients bearing small coding sequence mutations in the INS gene. Not all mutations in the INS gene cause the autosomal dominant Mutant INS-gene-induced Diabetes of Youth (MIDY) syndrome, but most missense m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Ming, Hodish, Israel, Haataja, Leena, Lara-Lemus, Roberto, Rajpal, Gautam, Wright, Jordan, Arvan, Peter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967602/
https://ncbi.nlm.nih.gov/pubmed/20724178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2010.07.001
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